Radicicol, HSP90 inhibitor, 1mg, CAS# 12772-57-5
$50.00
(1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione Purity: 99% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2102-1mg-EA
Radicicol, HSP90 inhibitor, 1mg, CAS# 12772-57-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsRadicicol inhibits heat shock protein 90 (Hsp90) activity by binding to the ATP-binding pocket.1 In cells Hsp90 client proteins such as Raf kinase2, HIF-1α3 and estrogen receptor4 are destabilized and proteolytically degraded. Inhibits expression of COX-2 without affecting COX-1 expression in LPS-stimulated macrophages (IC50=27 nM).5 Inhibits angiogenesis.6
CAS Number: 12772-57-5
Manufacturer Part Number/SKU: 10-2102-1mg-EA
Tags: Focus Biomolecules