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Nicotinamide, SIRT1 inhibitor/essential nutrient, 5g, CAS# 98-92-0

$40.00
Pyridine-3-carboxylic acid amide Purity: >99% by HPLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-2840-5g-EA
Nicotinamide, SIRT1 inhibitor/essential nutrient, 5g, CAS# 98-92-0 is available to buy in increments of 1

Product Details

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Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions.1 Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 µM)2, but is quickly converted to NAD+ in cells3. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation.4 Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs).5

CAS Number: 98-92-0

Manufacturer Part Number/SKU: 10-2840-5g-EA

Tags: Focus Biomolecules