L6H21, MDL/TLR4 interaction inhibitor, 5mg, CAS# 24533-47-9

L6H21, MDL/TLR4 interaction inhibitor, 5mg, CAS# 24533-47-9

4-Bromo-A23187, Ca2+ ionophore (non-fluorescent), 1mg, CAS# 76455-48-6

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VE-821, ATR inhibitor, 5mg, CAS# 1232410-49-9

$80.00
3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-5589-5mg-EA
VE-821, ATR inhibitor, 5mg, CAS# 1232410-49-9 is available to buy in increments of 1

Product Details

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VE-821 is a potent and selective ATP-competitive ATR (Ataxia-telangiectasia and Rad3-related protein) inhibitor, Ki=13 nM.1 Increases the sensitivity of pancreatic2 and ovarian3 cancer cells to radiation and chemotherapy. Increased replication stress induced by PARP inhibitors or chemotherapeutic agents increases sensitivity to VE-821 in neuroblastoma cells.4 Enhances the cytotoxicity of DNA damaging agents.5

CAS Number: 1232410-49-9

Manufacturer Part Number/SKU: 10-5589-5mg-EA

Tags: Focus Biomolecules