SN-38, DNA topoisomerase I inhibitor, 50mg, CAS# 86639-52-3
$300.00
7-Ethyl-10-hydroxycamptothecin Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2425-50mg-EA
SN-38, DNA topoisomerase I inhibitor, 50mg, CAS# 86639-52-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsActive metabolite of CPT-11 that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).
CAS Number: 86639-52-3
Manufacturer Part Number/SKU: 10-2425-50mg-EA
Tags: Focus Biomolecules