L-Cycloserine, Sphingolipid biosynthesis inhibitor, 100mg, CAS# 339-72-0
$140.00
(S)-4-Amino-3-isoxaolidinone Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2280-100mg-EA
L-Cycloserine, Sphingolipid biosynthesis inhibitor, 100mg, CAS# 339-72-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsL-Cycloserine down-regulates sphingolipid biosynthesis via inhibition of serine palmitoyltransferase (3-ketodihydrosphingosine synthetase).1 The L isomer was shown to be 100-fold more potent than the D isomer at inhibition of the brain microsomal enzyme.1 It is a useful pharmacological agent for lowering sphingolipid levels in cells2 as well as in animal models3. Inhibition of de novo ceramide biosynthesis with L-cycloserine positively affected the senescent phenotype, restoring neuronal signaling and reducing mitochondrial dysfunction in a cortical neuronal model of senescence.4
CAS Number: 339-72-0
Manufacturer Part Number/SKU: 10-2280-100mg-EA
Tags: Focus Biomolecules