BMS-309403, FABP4 inhibitor, 25mg, CAS# 300657-03-8
$215.00
2-[3-[2-(5-Ethyl-3,4-diphenylpyrazol-1-yl)phenyl]phenoxy]acetic acid Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4762-25mg-EA
BMS-309403, FABP4 inhibitor, 25mg, CAS# 300657-03-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsBMS-309403 is a potent (Ki <2 nM FABP4, Ki = 250 nM FABP3, Ki = 350 nM FABP5) and selective inhibitor of the fatty-acid-binding protein aP2 (FABP4).1,2 It demonstrated marked reductions in atherosclerotic lesions in an Apoe-/- mouse model and improved glucose metabolism, reduced inflammation, and increased insulin sensitivity in a Lepob/ob mouse model. BMS-309403 stimulated glucose uptake in myotubes via activation of AMPK.3 It decreased ER stress-associated inflammation in skeletal muscle4 and suppressed inflammation and oxidative stress in mouse and cell models of acute lung injury5.
CAS Number: 300657-03-8
Manufacturer Part Number/SKU: 10-4762-25mg-EA
Tags: Focus Biomolecules