LDN-193189_HCl, ALK2 / ALK3 inhibitor, 25mg, CAS# 1435934-00-1
$235.00
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline dihydrochloride Purity: 99% by HPLC (Agilent Poroshell 120 C18 Purity: 80/20 MeOH/water with 0.05% TFA; 0.8 ml/min) NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4764-25mg-EA
LDN-193189_HCl, ALK2 / ALK3 inhibitor, 25mg, CAS# 1435934-00-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsLDN-193189 2HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripotent stem cells.2-3 LDN-193189 HCl has also been used to examine the role of osteogenesis in prostate tumor metastases in bone.4
CAS Number: 1435934-00-1
Manufacturer Part Number/SKU: 10-4764-25mg-EA
Tags: Focus Biomolecules