ZM-447439, Aurora B kinase inhibitor, 25mg, CAS# 331771-20-1
$175.00
N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide Purity: 98% by TLC [10% methanol in methylene chloride; Rf = 0.30] Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1037-25mg-EA
ZM-447439, Aurora B kinase inhibitor, 25mg, CAS# 331771-20-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsZM-447439 is a selective ATP-competitive inhibitor of Aurora kinase B1 (IC50 = 50 nM, Aur A IC50 = 1 µM, Aur C IC50 = 250 nM at physiological ATP concentrations2, Ref.1 lists Aur A IC50 = 110nM and Aur B IC50 = 113nM). It did not significantly inhibit a panel of 14 other kinases including mitotic kinases CDK1 and PLK1. It prevents chromosome alignment, spindle checkpoint function and cytokinesis.1,2
CAS Number: 331771-20-1
Manufacturer Part Number/SKU: 10-1037-25mg-EA
Tags: Focus Biomolecules