Vismodegib, Sonic Hedgehog signaling pathway inhibitor, 5mg, CAS# 879085-55-9
$60.00
2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide Purity: 99% by TLC and HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2182-5mg-EA
Vismodegib, Sonic Hedgehog signaling pathway inhibitor, 5mg, CAS# 879085-55-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent and selective Hedgehog (Hh) pathway signaling inhibitor antagonizing SMO with a Ki of 1.3 nM).1 Alters intracellular Ca2+ homeostasis and inhibits growth of cisplatin-resistant lung cancer cells.2 Inhibits two ABC transporters, ABCG2/BCRP and ABCB1/Pgp, IC50s=1.4 and 3.0 μM respectively.3 Clinically useful for the treatment of basal cell carcinoma.4 Inhibits proliferation and induces apoptosis in colon cancer cell lines.
CAS Number: 879085-55-9
Manufacturer Part Number/SKU: 10-2182-5mg-EA
Tags: Focus Biomolecules