ML241, p97 AAA ATPase inhibitor, 5mg, CAS# 1346528-06-0
$90.00
N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine Purity: 98% by HPLC NMR (conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1555-5mg-EA
ML241, p97 AAA ATPase inhibitor, 5mg, CAS# 1346528-06-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3
CAS Number: 1346528-06-0
Manufacturer Part Number/SKU: 10-1555-5mg-EA
Tags: Focus Biomolecules