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Verrucarin A, Steroid receptor coactivator-3 inhibitor, 1mg, CAS# 3148-09-2

$130.00
Purity: >98% by HPLC Purity: NMR (conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3564-1mg-EA
Verrucarin A, Steroid receptor coactivator-3 inhibitor, 1mg, CAS# 3148-09-2 is available to buy in increments of 1

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A macrocyclic trichothecene mycotoxin from Myrothecium sp. It is a potent and selective inhibitor of the steroid receptor coactivator-3 and selectively down-regulates its expression.1 It is cytotoxic to multiple types of cancer cells at low nM concentrations (IC50=4.9 nM for HepG2 cells) but not toward normal liver cells.1,2 It enhances TNFα-induced3 and TRAIL-induced apoptosis4. It reduces phosphorylation of IREα and inhibits tunicamycin-induced ER stress in FaO rat liver cells.5

CAS Number: 3148-09-02

Manufacturer Part Number/SKU: 10-3564-1mg-EA

Tags: Focus Biomolecules