UNC0379, SETD8 inhibitor, 5mg, CAS# 1620401-82-2
$50.00
6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)-pentyl)quinazolin-4-amine Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4870-5mg-EA
UNC0379, SETD8 inhibitor, 5mg, CAS# 1620401-82-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsUNC0379 is an inhibitor of the lysine methyltransferase SETD8 with selectivity over 15 other methyltransferases.1 IC50's = 7.3 µM in a radioactive methyl transfer assay and 9.0 µM in an MCE assay. UNC0379 treatment of SY5Y and NGP neuroblastoma cell lines lead to activation of p53 and decreased tumor growth in an ex-vivo tumorigenicity assay.2
CAS Number: 1620401-82-2
Manufacturer Part Number/SKU: 10-4870-5mg-EA
Tags: Focus Biomolecules