SCR-1481B1, Gasdermin D inhibitor, 1mg, CAS# 1174161-86-4
$30.00
[3-[[4-(2-Amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]carbamoyl]-5-(4-fluorophenyl)-4-oxopyridin-1-yl]methyl dihydrogen phosphate;di 2-amino-2-(hydroxymethyl)propane-1,3-diol salt Purity: >98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3971-1mg-EA
SCR-1481B1, Gasdermin D inhibitor, 1mg, CAS# 1174161-86-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSCR-1481B1 is an inhibitor of HGFR (Met) and VEGFR kinases.1 SCR-1481B1 potently suppresses gasdermin D-mediated pyroptosis via targeting of the oligomerization interface I.2 Active in vivo in a mouse model of sepsis. SCR-1481B1 acts synergistically with another gasdermin D inhibitor, Cefcapene pivoxil (Cat #10-3972), and a PD-L1 antibody to significantly enhance the antitumor activity of anti-PD-L1 therapy.
CAS Number: 1174161-86-4
Manufacturer Part Number/SKU: 10-3971-1mg-EA
Tags: Focus Biomolecules