UH15-38·2HCl, RIP3K inhibitor, 5mg, CAS# 2540881-21-6
$80.00
3-(3-Hydroxyphenyl)-1-methyl-7-[3-(4-methylpiperazin-1-yl)anilino]-1,6-naphthyridin-2-one dihydrochloride Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4862-5mg-EA
UH15-38·2HCl, RIP3K inhibitor, 5mg, CAS# 2540881-21-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsUH15-38 is a potent (IC50 = 20 nM) inhibitor of RIPK3 with excellent cellular activity. It blocked TNF-induced necroptosis in primary mouse embryonic fibroblasts (IC50 = 98 nM). UH15-38 selectively blocked influenza A-induced necroptosis over apoptosis in mouse alveolar epithelial cells, mouse embryonic fibroblasts, and human M29 cells at nanomolar levels. It attenuated influenza A-induced lung injury and lethality in vivo.
CAS Number: 2540881-21-6
Manufacturer Part Number/SKU: 10-4862-5mg-EA
Tags: Focus Biomolecules