TETi76 ester, TET inhibitor, 10mg, CAS# 1451750-73-4
$75.00
Diethyl 2-hydroxy-4-methylenepentanedioate Purity: >98% TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4041-10mg-EA
TETi76 ester, TET inhibitor, 10mg, CAS# 1451750-73-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCell permeable inhibitor of TET dioxygenases (IC50s: TET1 = 1.5 µM; TET2 = 9.4 µM; TET3 = 8.8 µM), indirect (via cytosine hydroxymethylation) erasers of DNA methylation.1,2 TET2 is frequently mutated in myeloid neoplasms - TET2 inhibition with TETi76 restricted clonal outgrowth and induced apoptosis of TET2 mutants but not normal hematopoietic precursor cells in vitro and in vivo.
CAS Number: 1451750-73-4
Manufacturer Part Number/SKU: 10-4041-10mg-EA
Tags: Focus Biomolecules