Manufacturer: Focus Biomolecules
A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.
CAS Number: 307543-71-1
Manufacturer Part Number/SKU: 10-1510-25mg-EA
Tags: Focus Biomolecules