NSC47924, PHLP phosphatase inhibitor / Laminin inhibitor, 25mg, CAS# 6638-24-0
$200.00
1-((4-Methoxyanilino)methyl)-2-naphthol Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1562-25mg-EA
NSC47924, PHLP phosphatase inhibitor / Laminin inhibitor, 25mg, CAS# 6638-24-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent inhibitor of the Leucine-rich repeat protein phosphatase (PHLPP) an enzyme which is a negative regulator of Akt and PKC (IC50=4 mM).1 Increases AKT signaling in cells and prevents apoptosis. Also inhibits the 67 kDa laminin receptor (LR) interaction with laminin (LM) and selectively blocks LR-293 cell adhesion to LM IC50=19.35 mM) impairing cell migration and invasion.2 Affects 37/67 kDa LR cell surface localization and interaction with cellular prion protein.3
CAS Number: 6638-24-0
Manufacturer Part Number/SKU: 10-1562-25mg-EA
Tags: Focus Biomolecules