ST-034307, Adenylate cyclase 1 inhibitor, analgesic activity, 25mg, CAS# 133406-29-8
$250.00
6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one Purity: 98% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1620-25mg-EA
ST-034307, Adenylate cyclase 1 inhibitor, analgesic activity, 25mg, CAS# 133406-29-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA novel selective adenylyl cyclase 1 (AC1) inhibitor, IC50=2.3 μM . Inhibits calcium2+-stimulated cAMP accumulation in HEK cells stably transfected with AC11. It was also shown to inhibit AC1 stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells. It enhanced μ-opioid receptor-mediated inhibition of AC1 but it blocked heterologous sensitization of AC1 caused by chronic μ-opioid receptor activation.1 Displays analgesic properties in a mouse model of inflammatory pain.1
CAS Number: 133406-29-8
Manufacturer Part Number/SKU: 10-1620-25mg-EA
Tags: Focus Biomolecules