NG-497, Human ATGL inhibitor, 25mg, CAS# 2598242-66-9

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SRT1720_HCl, SIRT1 activator, 25mg, CAS# 1001645-58-4

$240.00
N-[2-[3-(Piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide hydrochloride Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4628-25mg-EA
SRT1720_HCl, SIRT1 activator, 25mg, CAS# 1001645-58-4 is available to buy in increments of 1

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SIRT1 activator (EC1.5 = 0.16 µM, max activation = 781%).1 It reduced glucose levels and hyperinsulinemia in DIO, Lepob/ob mice and Zucker fa/fa rats. SRT1720 enhanced endurance running and protected against diet-induced obesity and insulin resistance via enhancement of oxidative metabolism in skeletal muscle, liver, and brown adipose tissue.2 It induced mitochondrial biogenesis in oxidant-induced renal proximal tube cell injury.3 SRT1720 repressed circadian clock gene expression and decreased H3 K9/K14 acetylation in a time-specific manner.4 It attenuated angiotensin II-induced atherosclerosis by inhibiting the vascular inflammatory response.5

CAS Number: 1001645-58-4

Manufacturer Part Number/SKU: 10-4628-25mg-EA

Tags: Focus Biomolecules