SR1078, ROR agonist, 10mg, CAS# 1246525-60-9
$70.00
N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4066-10mg-EA
SR1078, ROR agonist, 10mg, CAS# 1246525-60-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsAgonist of the orphan nuclear receptors RORα and RORγ.1 It attenuated intrapancreatic pathological changes in mouse models of chronic pancreatitis via restoration of the circadian stabilizing loop.2 SR1078 stimulation of RORα restored clock protein BMAL1 expression and oscillation and blocked MYCN-mediated neuroblastoma growth.3 It reduced repetitive behavior is a mouse model of autism suggesting a potential therapeutic pathway for the disorder.4 SR1078 treatment lead to an increase in p53 levels and increased apoptosis in HepG2 cells.5
CAS Number: 1246525-60-9
Manufacturer Part Number/SKU: 10-4066-10mg-EA
Tags: Focus Biomolecules