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SM-164, Smac mimetic, 1mg, CAS# 957135-43-2

$190.00
(3S,3'S,6S,6'S,10aS,10'aS)-N,N'-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide Purity: 98% Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-5464-1mg-EA
SM-164, Smac mimetic, 1mg, CAS# 957135-43-2 is available to buy in increments of 1

Product Details

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Cell-permeable Smac (DIABLO) mimetic that inhibits caspase blockers XIAP, cIAP1, and cIAP2 (Ki = 36, <1, and <1.9 nM), thus inducing apoptosis.1-3 SM-164 sensitizes cancer cells to DNA damaging agents.4 It also prevents binding of Hsp70 to XIAP.5 At high concentrations, it causes lytic cell death that is neither apoptosis nor necroptosis.6

CAS Number: 957135-43-2

Manufacturer Part Number/SKU: 10-5464-1mg-EA

Tags: Focus Biomolecules