KL-001, Cryptochrome (CRY) activator, 5mg, CAS# 309928-48-1
$55.00
N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide Purity: 98% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1411-5mg-EA
KL-001, Cryptochrome (CRY) activator, 5mg, CAS# 309928-48-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA novel tool that specifically interacts with cryptochrome (CRY) preventing its ubiquitin-dependent degradation resulting in lengthening of the circadian period. KL-001-mediated CRY stabilization inhibits glucagon-induced gluconeogenesis in primary hepatocytes1. Binds to the FAD-binding pocket of CRY2 as determined by co-crystal structure2. Induces an increase in period along with simultaneous reduction in amplitude of circadian reporter expression3 in mammalian cells.
CAS Number: 309928-48-1
Manufacturer Part Number/SKU: 10-1411-5mg-EA
Tags: Focus Biomolecules