RECTAS, pre-mRNA splicing modulator, 5mg, CAS# 101862-47-9
$70.00
2-Chloro-N-(2-furanylmethyl)-9H-purin-6-amine Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5273-5mg-EA
RECTAS, pre-mRNA splicing modulator, 5mg, CAS# 101862-47-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsRECTAS, a pre-mRNA splice modulator (Rectifier of Aberrant Splicing), was discovered in a small molecule screen for compounds that rectify aberrant IKBKAP splicing in cells from patients with familial dysautonomia. RECTAS (2 mM) increased the expression of IKAP and restored tRNA modifications.1,2 It directly interacts with CDC-like kinases enhancing SRSF6 phosphorylation.2 A combination treatment with RECTAS and phenylbutyric acid was shown to restore DJ-1 protein and mitochondrial dysfunction in Parkinson's disease models.3
CAS Number: 101862-47-9
Manufacturer Part Number/SKU: 10-5273-5mg-EA
Tags: Focus Biomolecules