Quizartinib, FLT3 inhibitor, 5mg, CAS# 950769-58-1
$50.00
1-(5-(t-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea Purity: 98% by HPLC Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4813-5mg-EA
Quizartinib, FLT3 inhibitor, 5mg, CAS# 950769-58-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsQuizartinib is a potent and selective inhibitor of FLT3 (Kd = 1.6nM, IC50 = 0.56 nM MV4-11 cells).1 It is in clinical trials for treatment of Acute Myelogenous Leukemia (AML).2,3 Quizartinib priming resulted in prevention of myelosuppression in mice treated with 5-FU and Gemcitabine.4 Quizartinib showed significant reversal of ABCG2-mediated multidrug resistance (@ 3 µM) via antagonism of drug efflux function.5,6
CAS Number: 950769-58-1
Manufacturer Part Number/SKU: 10-4813-5mg-EA
Tags: Focus Biomolecules