PT-179, Thalidomide analog molecular glue, 25mg, CAS# 2924858-25-1
$250.00
2-(2,6-Dioxopiperidin-3-yl)-5-morpholin-4-ylisoindole-1,3-dione Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3963-25mg-EA
PT-179, Thalidomide analog molecular glue, 25mg, CAS# 2924858-25-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPT-179 is an orthogonal thalidomide analog that binds cereblon (CRBN: KD = 587 nM; pomalidomide KD = 500 nM) with greatly reduced off-target activity compared to pomalidomide. Pomalidomide induced differential expression of 1426 genes in MM.1S multiple myeloma cells compared to only 3 for PT-179. PT-179 is an interesting new tool for exploring CRBN-based therapeutics.
CAS Number: 2924858-25-1
Manufacturer Part Number/SKU: 10-3963-25mg-EA
Tags: Focus Biomolecules