N6022, S-Nitrosogluthione reductase inhibitor, 25mg, CAS# 1208315-24-5
$205.00
3-(5-(4-(1H-Imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4103-25mg-EA
N6022, S-Nitrosogluthione reductase inhibitor, 25mg, CAS# 1208315-24-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsN6022 is a potent and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) - IC50 = 20 nM1, 8 nM2. It demonstrated significant efficacy in a mouse models of ovalbumin-induced asthma, chronic obstructive pulmonary disease, and irritable bowel syndrome. N6022 was able to attenuate experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) via selective inhibition of pro-inflammatory CD4+ cells (TH1/TH17) while upregulating anti-inflammatory subsets of CD4+ cells (TH2/Treg) without causing lymphopenia.3
CAS Number: 1208315-24-5
Manufacturer Part Number/SKU: 10-4103-25mg-EA
Tags: Focus Biomolecules