NU7441, DNA-PK inhibitor, 25mg, CAS# 503468-95-9
$135.00
8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4810-25mg-EA
NU7441, DNA-PK inhibitor, 25mg, CAS# 503468-95-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsNU7441 is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK).1,2 It increased the toxicity of ionizing radiation and etoposide on SW620 human colon cancer lines via impeding DNA double-strand break repair.3 NU7441 also increased the radio/chemosensitivity of various other cancer cell lines.3-6 Reduces the frequency of NHEJ repair while enhancing the rate of HDR repair following CRISPR/Cas9-mediated gene editing.7
CAS Number: 503468-95-9
Manufacturer Part Number/SKU: 10-4810-25mg-EA
Tags: Focus Biomolecules