NSC697923, Ubiquitin E2 Conjugating enzyme inhibitor, 25mg, CAS# 343351-67-7
$160.00
2-[(Methylphenyl)sulfonyl]-5-nitrofuran Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1418-25mg-EA
NSC697923, Ubiquitin E2 Conjugating enzyme inhibitor, 25mg, CAS# 343351-67-7 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSelective inhibitor of E2 ubiquitin-conjugating enzyme, Ubc13-Uev1A. Does not inhibit UbcH5c activity. Impedes the formation of the Ubc13 and inhibits NF-κB activation in activated B cell-like diffuse large B-cell lymphoma (ABC-DLBCL) cells1. Blocks proliferation and survival of both ABC-DLBCL and germinal center B cell-like (GCB)-DLBCL cell lines, and survival of primary DLBCL cells. Acts via covalent bonding to E2 active site thiol2,3. Induces neuroblastoma cell death via activation of p53 and JNK4.
CAS Number: 343351-67-7
Manufacturer Part Number/SKU: 10-1418-25mg-EA
Tags: Focus Biomolecules