Monocrotaline, Pulmonary fibrosis inducer, 50mg, CAS# 315-22-0
$58.00
(3R,4R,5R)-4,5,8,10,12,13,13aR,13bR-octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2872-50mg-EA
Monocrotaline, Pulmonary fibrosis inducer, 50mg, CAS# 315-22-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsMonocrotaline is a naturally occurring pyrrolizidine alkaloid used to create an animal model of pulmonary arterial hypertension (PAH). It can mimic several important aspects of human PAH including vascular remodeling, proliferation of smooth muscle cells, endothelial dysfunction, production of inflammatory cytokines and right ventricle failure.1 Induces endoplasmic reticulum stress in a rat model of PAH.2 Induces sinusoidal obstruction syndrome, a form of drug-induced liver injury.3 May be used to establish a mouse model of pulmonary fibrosis.4
CAS Number: 315-22-0
Manufacturer Part Number/SKU: 10-2872-50mg-EA
Tags: Focus Biomolecules