MLS-544460, Eya2 phosphatase inhibitor, 5mg, CAS# 352336-36-8
$60.00
3-Fluoro-N-((E)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino)benzamide Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5332-5mg-EA
MLS-544460, Eya2 phosphatase inhibitor, 5mg, CAS# 352336-36-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsMLS-544460 is an allosteric inhibitor of the Eya2 tyrosine phosphatase (IC50=4.1 uM)1-2 which is ineffective against other tyrosine phosphatases including Eya3 and PTP1B. Treatment of patient-derived glioma stem cells induced loss of bipolar spindle formation along with G2/M cell cycle arrest. GSC proliferation was inhibited at concentrations 4 to 10-fold lower than normal brain cells.3 Treatment of Axolotls following amputation impairs limb regeneration indicating a role for Eya2 in vertebrate regeneration.4
CAS Number: 352336-36-8
Manufacturer Part Number/SKU: 10-5332-5mg-EA
Tags: Focus Biomolecules