Leu-Leu-OMe HBr, Lysosomal damaging agent, 20mg, CAS# 16689-14-8
$45.00
Leucyl-leucine methyl ester hydrobromide Purity: 98% by HPLC NMr (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3220-20mg-EA
Leu-Leu-OMe HBr, Lysosomal damaging agent, 20mg, CAS# 16689-14-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsLeu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
CAS Number: 16689-14-8
Manufacturer Part Number/SKU: 10-3220-20mg-EA
Tags: Focus Biomolecules