KNK437, Inhibits HSP70 expression, 5mg, CAS# 218924-25-5
$60.00
3-(1,3-Benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5561-5mg-EA
KNK437, Inhibits HSP70 expression, 5mg, CAS# 218924-25-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGFß signaling.3 Inhibits leukocyte integrin α4ß7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for ß7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg).5
CAS Number: 218924-25-5
Manufacturer Part Number/SKU: 10-5561-5mg-EA
Tags: Focus Biomolecules