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Kenpaullone, GSK-3ß/CDK/KLF4 inhibitor, 5mg, CAS# 142273-20-9

$80.00
9-Bromo-7,12-dihydro-indolo[3,2-d]benzazepine-6(5H-one Purity: >98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3028-5mg-EA
Kenpaullone, GSK-3ß/CDK/KLF4 inhibitor, 5mg, CAS# 142273-20-9 is available to buy in increments of 1

Product Details

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Inhibits GSK-3β (IC50=0.23 µM) as well as several cyclin-dependent kinases (CDKs), IC50=0.4, 0.68 and 0.85 µM for cdk1, cdk2 and cdk5 respectively.1-3 Induces pluripotent stem cells from somatic cells4 and increases direct neural conversion of human fibroblasts5 when used with other small molecules. Inhibits Kruppel-Like Factor 4 (KLF4) reducing autoimmune arthritis in the collagen-induced arthritis mouse model.6

CAS Number: 142273-20-9

Manufacturer Part Number/SKU: 10-3028-5mg-EA

Tags: Focus Biomolecules