JIB-04, pan-JUMONJI histone demethylase inhibitor, 25mg, CAS# 199596-05-9
$210.00
(E)-5-Chloro-2-(2-(phenyl(pyridine-2-yl)methylene)hydrazinyl)pyridine Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1618-25mg-EA
JIB-04, pan-JUMONJI histone demethylase inhibitor, 25mg, CAS# 199596-05-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA novel specific inhibitor of the Jumonji family of histone demethylases in vitro, in cancer cells and in tumors in vivo. IC50 = 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3 and JMJD2C respectively. Reduces tumor burden and prolongs life in a mouse model.1 Suppresses translation initiation and enhances mTOR inhibitor sensitivity.2 Inhibits the growth of temozolomide-resistant glioblastoma cells and crosses the blood brain barrier.3
CAS Number: 199596-05-9
Manufacturer Part Number/SKU: 10-1618-25mg-EA
Tags: Focus Biomolecules