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Isohelenin, NFkB inhibitor, 5mg, CAS# 470-17-7

$50.00
(3aR,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-5393-5mg-EA
Isohelenin, NFkB inhibitor, 5mg, CAS# 470-17-7 is available to buy in increments of 1

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A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFkB (complete inhibition at 5 mM)1 acting via inhibition of IKKb6. Isohelenin-mediated NFkB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6

CAS Number: 470-17-7

Manufacturer Part Number/SKU: 10-5393-5mg-EA

Tags: Focus Biomolecules