iJMJD6, Arginine demethylase JMJD6 inhibitor, 5mg, CAS# 899548-78-8
$75.00
3-(3H-Imidazo[4,5-c]pyridine-2-yl)-6-methylchromen-2-one Purity: >98% HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4039-5mg-EA
iJMJD6, Arginine demethylase JMJD6 inhibitor, 5mg, CAS# 899548-78-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibitor of the arginine demethylase JMJD6 (IC50 = 220 nM) with selectivity over other JmjC domain-containing proteins.1 Exhibited antiproliferative effects in HeLa (EC50 = 1.49 µM), SMCC7721 (EC50 = 9.37 µM), and MCF7 (EC50 = 9.53 µM) cells.2 Displayed no cytotoxicity towards normal cervical, liver, and breast epithelial cells. iJMJD6 significantly suppressed tumor growth in a HeLa, SMCC7721, MCF7, MDA-MB-231, U87, and HCT116 mouse xenograft models.2
CAS Number: 899548-78-8
Manufacturer Part Number/SKU: 10-4039-5mg-EA
Tags: Focus Biomolecules