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Elafibranor, PPARα/δ agonist, 5mg, CAS# 923978-27-2

$65.00
2-[2,6-Dimethyl-4-[(E)-3-(4-methylsulfanylphenyl)-3-oxoprop-1-enyl]phenoxy]-2-methylpropanoic acid Purity: 98% by HPLC NMr (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3901-5mg-EA
Elafibranor, PPARα/δ agonist, 5mg, CAS# 923978-27-2 is available to buy in increments of 1

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Elafibranor is a dual PPARalpha/delta agonist (EC50 PPARalpha = 10-20 nM; PPARdelta = 100-150 nM).1 It was able to decrease plasma triglycerides levels1, increase HDL cholesterol levels in human studies1, and improve hepatic and peripheral insulin sensitivity2. Elafibranor's antidiabetic effects in db/db were without the adverse cardiac effects seen in PPARgamma agonism.3 Elafibranor has also been shown to have therapeutic promise in the treatment of nonalcoholic steatohepatitis (NASH).4-6

CAS Number: 923978-27-2

Manufacturer Part Number/SKU: 10-3901-5mg-EA

Tags: Focus Biomolecules