CPI-444, Adenosine A2A receptor antagonist, 5mg, CAS# 1202402-40-1
$95.00
7-(5-methylfuran-2-yl)-3-[[6-[[(3S)-oxolan-3-yl]oxymethyl]pyridine-2-yl]triazolo[4,5-d]pyrimidin-5-amine Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4101-5mg-EA
CPI-444, Adenosine A2A receptor antagonist, 5mg, CAS# 1202402-40-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCPI-444 (1202402-40-1) is a potent (Ki = 3.54 nM) and selective adenosine A2A receptor antagonist. It blocked the induction of cAMP induced by NECA in HEK-293 cells with an IC50 = 17.03 nM. CPI-444 monotherapy or in combination with anti-PD-1, anti-PD-L1, and anti-CTLA-4 induced T-cell-mediated tumor responses, inhibited tumor growth, and enabled antitumor immune memory.1,2 Currently in clinical trials for multiple cancers.3
CAS Number: 1202402-40-1
Manufacturer Part Number/SKU: 10-4101-5mg-EA
Tags: Focus Biomolecules