Preladenant, Adenosine A2A receptor antagonist, 5mg, CAS# 377727-87-2
$70.00
4-(Furan-2-yl)-10-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4102-5mg-EA
Preladenant, Adenosine A2A receptor antagonist, 5mg, CAS# 377727-87-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPreladenant is a potent (Ki = 1.1nM) and selective (>1000-fold over other adenosine receptors) adenosine A2A antagonist.1 It has shown efficacy in rodent and primate models of Parkinsons disease without inducing dyskinesias and displays antidepressant effects.1-3 It has been shown that activation of the adenosine A2A receptor blocks the activation of immune cells and increases the number of regulatory T-cells.4-6 Currently in clinical trials as combination therapy with pembrolizumab.7
CAS Number: 377727-87-2
Manufacturer Part Number/SKU: 10-4102-5mg-EA
Tags: Focus Biomolecules