CIB-3b, Inhibitor of microRNA biogenesis, 25mg, CAS# 124811-87-6
$195.00
Ethyl 2-(4-methoxyphenyl)-5-methyl-1,3-oxazole-4-carboxylate Purity: >98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3923-25mg-EA
CIB-3b, Inhibitor of microRNA biogenesis, 25mg, CAS# 124811-87-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCIB-3b inhibits microRNA (miRNA) biogenesis via binding (KD = 10.42 nM) to transactivation response (TAR) RNA-binding protein 2 (TRBP), disrupting the TRBP-Dicer interaction, a critical element in pre-miRNA processing. It inhibited mi-R21 (EC50 = 1.38 µM) expression, a potent inducer of cellular EMT progression. CIB-3b inhibited hepatocarcinogenesis by blocking EMT in a mouse orthotopic transplantation model (SK-HEP-1 cells).
CAS Number: 124811-87-6
Manufacturer Part Number/SKU: 10-3923-25mg-EA
Tags: Focus Biomolecules