CCG-4986, RGS4 inhibitor, 5mg, CAS# 7134-19-2
$60.00
Methyl-N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoate Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1431-5mg-EA
CCG-4986, RGS4 inhibitor, 5mg, CAS# 7134-19-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCCG-4986 is the first selective non-peptide inhibitor of the regulator of G protein signaling protein subtype RGS4.1 It covalently2-3 modifies RGS4 by inhibiting its interaction with Gα (IC50 = 3-5 mM) and suppressing GTPase activity1. Intratympanic administration of CCG-4986 was shown to rescue cochlear injury and hearing loss induced by acoustic overexposure and represents a novel paradigm for the treatment of sensorineural hearing loss via pharmacological regulation of GPCR signaling.4 A novel tool for exploring the involvement of RGS4 in physiological processes.5
CAS Number: 7134-19-2
Manufacturer Part Number/SKU: 10-1431-5mg-EA
Tags: Focus Biomolecules