BTB-1, Mitotic kinesin Kif18A inhibitor, 10mg, CAS# 86030-08-2
$40.00
4-Chloro-2-nitro-1-(phenylsulfonyl)-benzene Purity: 98% by HPLC NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1543-10mg-EA
BTB-1, Mitotic kinesin Kif18A inhibitor, 10mg, CAS# 86030-08-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 mM.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5
CAS Number: 86030-08-02
Manufacturer Part Number/SKU: 10-1543-10mg-EA
Tags: Focus Biomolecules