Brequinar_sodium, Dihysroorotate dehydrogenase inhibitor, antiviral, 50mg, CAS# 96201-88-6
$275.00
6-Fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid sodium salt Purity: 99% by HPLC NMR Conforms Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3965-50mg-EA
Brequinar_sodium, Dihysroorotate dehydrogenase inhibitor, antiviral, 50mg, CAS# 96201-88-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsBrequinar sodium is an inhibitor of dihydroorotate dehydrogenase (DHODH)1,2 with IC50's between 0.2 and 5.8 µM in various cell lines3 and 20 nM in isolated enzyme4. It reduced leukemic cell burden, decreased levels of leukemia-initiating cells, and improved survival in human and mouse models of acute myeloid leukemia.4 Brequinar displayed broad antiviral activity against flaviviruses, positive-strand RNA alphaviruses, negative-strand RNA rhabdoviruses, Influenza A and B viruses, and HIV.5,6,7
CAS Number: 96201-88-6
Manufacturer Part Number/SKU: 10-3965-50mg-EA
Tags: Focus Biomolecules