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A-196, SUV420H1/H2 lysine methyltransferase inhibitor, 25mg, CAS# 1982372-88-2

$270.00
Cyclopentyl-(6,7-dichloro-4-pyridin-4-yl-phthalazin-1-yl)-amine Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4018-25mg-EA
A-196, SUV420H1/H2 lysine methyltransferase inhibitor, 25mg, CAS# 1982372-88-2 is available to buy in increments of 1

Product Details

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A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1(IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM). It substantially inhibited non-homologous end-joining (NHEJ)-directed DNA repair but not homology-directed repair(HDR) in cells treated with ionizing radiation. A-196 is active in cells and displayed no toxicity in several cell lines.

CAS Number: 1982372-88-2

Manufacturer Part Number/SKU: 10-4018-25mg-EA

Tags: Focus Biomolecules