This category covers everyday reagents for molecular and cell biology work. It includes buffers and buffer components such as Tris base, MOPS, CAPS, Bicine, glycine, 0.5 M EDTA solution at pH 8.0 and PBS tablets; detergents including Triton X-100, Tween 20, Tween 80, CHAPS and sodium deoxycholate; bovine serum albumin as Fraction V powder and 20 mg/ml solution; polymers like PEG 1000, PEG 8000 and Ficoll 400; and DNase- and RNase-free molecular biology grade water, along with enzymes, cofactors and amino acids. Pack sizes run from milligrams to kilograms and from milliliters to multi-liter containers.

Check the grade first: molecular biology grade material is tested for nucleases, while ultra pure and reagent grades are defined by each manufacturer's specification. Then compare purity, form (powder, solution or tablet), pack size against how fast you use the material, and storage conditions. Review the SDS before use and request a Certificate of Analysis when you need lot-level records.

Molecular Biology Reagents: common questions

What are life science or biological reagents?

Biological or life science reagents are the chemicals and biological materials used to prepare, grow, separate or analyze cells, proteins and nucleic acids. Examples include buffers, detergents, salts, proteins such as BSA, enzymes, nucleotides and cofactors, and specially purified water. They are graded by purity and testing, which determines whether they suit routine work or sensitive applications.

What does molecular biology grade mean?

Molecular biology grade generally means the material has been tested for, and found free of detectable, DNase, RNase and often protease activity, so it will not degrade DNA, RNA or proteins in your samples. The exact tests vary by manufacturer, so check the specification sheet or Certificate of Analysis for what was tested and the limits used.

What is a lyophilized reagent?

A lyophilized reagent has been freeze-dried: frozen, then dried under vacuum so the water sublimes. The dry product is usually more stable in storage and shipping than a liquid. Before use it is reconstituted with the volume and type of liquid the manufacturer specifies. After reconstitution, follow the stated storage conditions and shelf life.

Can I get pricing for bulk quantities of reagents?

Yes. Volume and quote pricing is available through the Contact Us page, and approved business accounts can pay by purchase order. Chemicals ship only to business addresses, with a company name required at checkout. Many items ship directly from the manufacturer, so lead times vary by item.

Molecular Biology Reagents

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  1. Leupeptin Hemisulfate, 25 MG CAS# 103476-89-7
    Manufacturer: Research Products International
    Mol. Wt:475.6 Common Name: Formula: C20H38N6O4 - 1/2H2SO4 Dimensions: 1.25 x 1.75 x 1.25, Weight: 0.03, Cas#: 103476-89-7 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $189.85
  2. Esculin, 25 Grams CAS# 531-75-9
    Manufacturer: Research Products International
    Mol. Wt:340.28 Common Name: Formula: C15H16O9 - xH2O Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: 531-75-9 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $152.40
  3. PMSF [Phenylmethylsulfonyl fluoride], 250 Grams CAS# 329-98-6
    Manufacturer: Research Products International
    Mol. Wt:174.2 Common Name: Phenylmethylsulfonyl fluoride Formula: C7H7FO2S Dimensions: 3.00 x 6.00 x 3.00, Weight: 1.18, Cas#: 329-98-6 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $1,990.25
  4. HEPES, Sodium Salt, N-, 2-Hydroxyethyl, piperazine-N'-, 2-ethanesulfonic acid, , 1 Kilogram CAS# 75277-39-3
    Manufacturer: Research Products International
    Mol. Wt:260.3 Common Name: N-(2-Hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid) Formula: C8H17N2O4SNa Dimensions: 4.88 x 6.00 x 4.88, Weight: 2.41, Cas#: 75277-39-3 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $564.95
  5. MES Monohydrate [2-(N-Morpholino)-ethanesulfonic acid], 5 Kilograms CAS# 145224-94-8
    Manufacturer: Research Products International
    Mol. Wt:213.24 Common Name: 2-(N-Morpholino)ethanesulfonic acid Formula: C6H13NO4S • H2O Dimensions: 10.00 x 7.50 x 10.00, Weight: 12.4, Cas#: 145224-94-8 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $3,942.75
  6. TRIS Hydrochloride, Tris, hydroxymethyl, aminomethane HCl, 250 Grams CAS# 1185-53-1
    Manufacturer: Research Products International
    Mol. Wt:157.6 Common Name: Tris(hydroxymethyl) aminomethane hydrochloride Formula: C4H11NO3-HCl Dimensions: 3.50 x 3.75 x 3.50, Weight: 0.64, Cas#: 1185-53-1 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $71.80
  7. DL-Thioctic Acid, DL-a-Lipoic acid, 5 Grams CAS# 1077-28-7
    Manufacturer: Research Products International
    Product usually ships within 24 hours. This product is sold for laboratory research use only. Mol. Wt:206.3 Common Name: DL-a-Lipoic acid Formula: C8H14O2S2 Dimensions: 3.38 x 4.63 x 3.38, Weight: 0.11, Cas#: 1077-28-7 Research or further manufacturing u (1 per EA)
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    $83.45
  8. HEPES, Sodium Salt, N-, 2-Hydroxyethyl, piperazine-N'-, 2-ethanesulfonic acid, , 5 Kilograms CAS# 75277-39-3
    Manufacturer: Research Products International
    Mol. Wt:260.3 Common Name: N-(2-Hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid) Formula: C8H17N2O4SNa Dimensions: 10.00 x 11.25 x 10.00, Weight: 12.72, Cas#: 75277-39-3 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $1,708.20
  9. Myricetin, 500 MG CAS# 529-44-2
    Manufacturer: Research Products International
    Product usually ships within 24 hours. This product is sold for laboratory research only. Mol. Wt:318.24 Common Name: Formula: C15H10O8 Dimensions: 1.25 x 1.75 x 1.25, Weight: 0.03, Cas#: 529-44-2 Research or further manufacturing use only, not for food (1 per EA)
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    $1,019.80
  10. Methyl-a-D-Mannopyranoside, 100 Grams CAS# -468506
    Manufacturer: Research Products International
    Mol. Wt:194.18 Common Name: Methyl-α-D-Mannopyranoside Formula: C7H14O6 Dimensions: 3.50 x 3.75 x 3.50, Weight: 0.32, Cas#: -468506 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $126.30
  11. TAPS, Tris, hydroxymethyl, -3-aminopropanesulfonic acid, Free Acid, 1 Kilogram CAS# 299115-38-6
    Manufacturer: Research Products International
    Mol. Wt:243.3 Common Name: Tris(hydroxymethyl)-3-aminopropanesulfonic acid Formula: C7H17NO6S Dimensions: 4.88 x 6.00 x 4.88, Weight: 2.41, Cas#: 299115-38-6 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $126.30
  12. Cefpodoxime Free Acid, 5 Grams CAS# 80210-62-4
    Manufacturer: Research Products International
    Mol. Wt:427.46 g/mol Common Name: Formula: C15H17N5O6S2 Dimensions: 3.38 x 4.63 x 3.38, Weight: 0.11, Cas#: 80210-62-4 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $665.15
  13. MUG, 4-Methylumbelliferyl-B-D-glucuronide Trihydrate, 1 Gram CAS# 6160-80-1
    Manufacturer: Research Products International
    Mol. Wt:406.4 Common Name: 4-Methylumbelliferyl-β-D-glucuronide Trihydrate Formula: C16H16O9-3H2O Dimensions: 1.25 x 1.75 x 1.25, Weight: 0.04, Cas#: 6160-80-1 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $222.20
  14. CHAPS, 3-, 3-Cholamidopropyl, -dimethylammonio, -1-propanesulfonate, 10 Grams CAS# 26926106
    Manufacturer: Research Products International
    Mol. Wt:614.9 Common Name: 3-[(Cholamidopropyl) dimethylammonio]-1-propanesulfonate Formula: C32H58N2O7S Dimensions: 3.38 x 4.63 x 3.38, Weight: 0.13, Cas#: 26926106 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $285.20
  15. Tricine, Ultra Pure, N-Tris , Hydroxymethyl, Methyl, Glycine, 1 Kilogram
    Manufacturer: Research Products International
    Mol. Wt:179.17 Common Name: N-[Tris (Hydroxymethyl) Methyl] Glycine Formula: C6H13NO5 Dimensions: 4.88 x 6.00 x 4.88, Weight: 2.41, Cas#: 1389475 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $632.80
  16. CHES, 2-, N-Cyclohexylamino, ethanesulfonic acid, 100 Grams CAS# 103-47-9
    Manufacturer: Research Products International
    Purity: >99% pKa (25°C): 9.3-9.7 pH Range: 8.6-10.0 Soluble in: Water Store at: Room Temperature Product usually ships within 24 hours. This product is sold for laboratory research use only. Mol. Wt:207.3 Common Name: 2-(N-Cyclohexylamino)ethanesulfonic a (1 per EA)
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    $65.00
  17. Methyl-a-D-Mannopyranoside, 25 Grams CAS# -468506
    Manufacturer: Research Products International
    Mol. Wt:194.18 Common Name: Methyl-α-D-Mannopyranoside Formula: C7H14O6 Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: -468506 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $46.00
  18. bis-TRIS, bis-, 2-hydroxyethyl, aminotris, hydroxymethyl, methane, 1 Kilogram CAS# 6976-37-0
    Manufacturer: Research Products International
    pH (1%, water @ 25°C): 8.8-9.6 pKa (@ 25°C): 6.45-6.65 Melting Range: 102-106°C Water (KF): <1.0% Mol. Wt:209.2 Common Name: bis(2-Hydroxyethyl)aminotris (hydroxymethyl)methane Formula: C8H19NO5 Dimensions: 4.88 x 7.25 x 4.88, Weight: 2.42, Cas#: 6976-37- (1 per EA)
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    $639.05
  19. Glycylglycine, Gly-Gly, 1 Kilogram CAS# 556-50-3
    Manufacturer: Research Products International
    Purity: >99% pKa (25°C): 8.0 pH range: 7.5 Heavy metals: >0.002% Soluble in: Water Store at: Room Temperature Usually ships within 24 hours. This product is sold for laboratory research use only. Mol. Wt:132.1 Common Name: Gly-Gly Formula: C4H8N2O3 Di (1 per EA)
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    $620.30
  20. Hypoxanthine, Monosodium Salt, 500 Grams CAS# 45738-97-4
    Manufacturer: Research Products International
    Purity:>98% Store at room temperature Soluble in water Cas No. 45738-97-4 Usually ships within 24 hours. Mol. Wt:158.11 Common Name: Formula: C5H4N4ONa Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.24, Cas#: 45738-97-4 Research or further manufacturing use (1 per EA)
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    $1,062.95
  21. DTT, DL-Dithiothreitol, , Cleland's Reagent, , 100 Grams CAS# 3483-12-3
    Manufacturer: Research Products International
    Mol. Wt:154.25 Common Name: [DL-Dithiothreitol] (Cleland's Reagent)] Formula: C4H10O2S2 Dimensions: 3.75 x 3.50 x 3.50, Weight: 0.31, Cas#: 3483-12-3 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $714.20
  22. Benzamidine Hydrochloride, 25 Grams CAS# 1670-14-0
    Manufacturer: Research Products International
    Mol. Wt:156.6 Common Name: Formula: C7H8N2-HCl Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: 1670-14-0 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $73.50
  23. CHES, 2-, N-Cyclohexylamino, ethanesulfonic acid, 1 Kilogram CAS# 103-47-9
    Manufacturer: Research Products International
    Purity: >99% pKa (25°C): 9.3-9.7 pH Range: 8.6-10.0 Soluble in: Water Store at: Room Temperature Product usually ships within 24 hours. This product is sold for laboratory research use only. Mol. Wt:207.3 Common Name: 2-(N-Cyclohexylamino)ethanesulfonic a (1 per EA)
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    $587.65
  24. STET Buffer 1X Solution, Sodium Chloride-TRIS-EDTA-Triton, 500 Milliliters
    Manufacturer: Research Products International
    Mol. Wt: Common Name: Sodium Chloride-TRIS-EDTA-Triton Formula: Dimensions: 3.50 x 8.50 x 3.50 Weight: 2.4 - Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $46.00
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