This category covers everyday reagents for molecular and cell biology work. It includes buffers and buffer components such as Tris base, MOPS, CAPS, Bicine, glycine, 0.5 M EDTA solution at pH 8.0 and PBS tablets; detergents including Triton X-100, Tween 20, Tween 80, CHAPS and sodium deoxycholate; bovine serum albumin as Fraction V powder and 20 mg/ml solution; polymers like PEG 1000, PEG 8000 and Ficoll 400; and DNase- and RNase-free molecular biology grade water, along with enzymes, cofactors and amino acids. Pack sizes run from milligrams to kilograms and from milliliters to multi-liter containers.

Check the grade first: molecular biology grade material is tested for nucleases, while ultra pure and reagent grades are defined by each manufacturer's specification. Then compare purity, form (powder, solution or tablet), pack size against how fast you use the material, and storage conditions. Review the SDS before use and request a Certificate of Analysis when you need lot-level records.

Molecular Biology Reagents: common questions

What are life science or biological reagents?

Biological or life science reagents are the chemicals and biological materials used to prepare, grow, separate or analyze cells, proteins and nucleic acids. Examples include buffers, detergents, salts, proteins such as BSA, enzymes, nucleotides and cofactors, and specially purified water. They are graded by purity and testing, which determines whether they suit routine work or sensitive applications.

What does molecular biology grade mean?

Molecular biology grade generally means the material has been tested for, and found free of detectable, DNase, RNase and often protease activity, so it will not degrade DNA, RNA or proteins in your samples. The exact tests vary by manufacturer, so check the specification sheet or Certificate of Analysis for what was tested and the limits used.

What is a lyophilized reagent?

A lyophilized reagent has been freeze-dried: frozen, then dried under vacuum so the water sublimes. The dry product is usually more stable in storage and shipping than a liquid. Before use it is reconstituted with the volume and type of liquid the manufacturer specifies. After reconstitution, follow the stated storage conditions and shelf life.

Can I get pricing for bulk quantities of reagents?

Yes. Volume and quote pricing is available through the Contact Us page, and approved business accounts can pay by purchase order. Chemicals ship only to business addresses, with a company name required at checkout. Many items ship directly from the manufacturer, so lead times vary by item.

Molecular Biology Reagents

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  1. ADP, Adenosine-5'-diphosphate, disodium salt dihydrate, 10 Grams CAS# 16178-48-6
    Manufacturer: Research Products International
    Mol. Wt:507.2 Common Name: Adenosine-5'-diphosphate, disodium salt, dihydrate Formula: C10H13N5O10P2Na2-2H2O Dimensions: 3.38 x 4.63 x 3.38, Weight: 0.13, Cas#: 16178-48-6 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $268.45
  2. TES, Sodium Salt, 2-Tris, hydroxymethyl, methyl-2-amino-1-ethanesulfonic acid, sodium salt, 25 Grams CAS# 70331-82-7
    Manufacturer: Research Products International
    pKa (25°C): 7.4-7.6 pH Range: 6.8-8.2 Heavy Metals: <0.0001% Mol. Wt:251.23 Common Name: 2-Tris(hydroxymethyl) methyl-2-amino-1-ethanesulfonic acid, sodium salt Formula: C6H14NO6SNa Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: 70331-82-7 Researc (1 per EA)
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    $105.00
  3. TAPS, Tris, hydroxymethyl, -3-aminopropanesulfonic acid, Free Acid, 5 Kilograms CAS# 299115-38-6
    Manufacturer: Research Products International
    Mol. Wt:243.3 Common Name: Tris(hydroxymethyl)-3-aminopropanesulfonic acid Formula: C7H17NO6S Dimensions: 10.00 x 7.50 x 10.00, Weight: 12.43, Cas#: 299115-38-6 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $578.30
  4. Methyl-a-D-Mannopyranoside, 500 Grams CAS# -468506
    Manufacturer: Research Products International
    Mol. Wt:194.18 Common Name: Methyl-α-D-Mannopyranoside Formula: C7H14O6 Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.24, Cas#: -468506 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $489.50
  5. 6-Mercaptopurine, 10 Grams CAS# 6112-76-1
    Manufacturer: Research Products International
    Mol. Wt:170.2 Common Name: Formula: C5H4N4S-H2O Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: 6112-76-1 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $137.10
  6. TES, Free Acid, 2-Tris, hydroxymethyl, -methyl-2-amino 1-ethanesulfonic acid, 500 Grams CAS# 7365-44-8
    Manufacturer: Research Products International
    Mol. Wt:229.25 Common Name: 2-Tris(hydroxymethyl)-methyl-2-amino 1-ethanesulfonic acid Formula: C6H15NO6S Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.23, Cas#: 7365-44-8 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $311.30
  7. bis-TRIS, bis-, 2-hydroxyethyl, aminotris, hydroxymethyl, methane, 500 Grams CAS# 6976-37-0
    Manufacturer: Research Products International
    pH (1%, water @ 25°C): 8.8-9.6 pKa (@ 25°C): 6.45-6.65 Melting Range: 102-106°C Water (KF): <1.0% Mol. Wt:209.2 Common Name: bis(2-Hydroxyethyl)aminotris (hydroxymethyl)methane Formula: C8H19NO5 Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.23, Cas#: 6976-37- (1 per EA)
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    $383.95
  8. TES, Sodium Salt, 2-Tris, hydroxymethyl, methyl-2-amino-1-ethanesulfonic acid, sodium salt, 100 Grams CAS# 70331-82-7
    Manufacturer: Research Products International
    pKa (25°C): 7.4-7.6 pH Range: 6.8-8.2 Heavy Metals: <0.0001% Mol. Wt:251.23 Common Name: 2-Tris(hydroxymethyl) methyl-2-amino-1-ethanesulfonic acid, sodium salt Formula: C6H14NO6SNa Dimensions: 3.50 x 3.75 x 3.50, Weight: 0.32, Cas#: 70331-82-7 Researc (1 per EA)
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    $226.45
  9. AMPSO, 3-, , 1,1-Dimethyl-2-hydroxyethyl, amino, -2-hydroxypropanesulfonic acid, 25 Grams CAS# 68399-79-1
    Manufacturer: Research Products International
    Mol. Wt:227.3 Common Name: 3-(1,1-Dimethyl-2 hydroxyethyl) amino-2-hydroxypropanesulfonic acid Formula: C7H17NO5S Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: 68399-79-1 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $76.90
  10. MUG [4-Methylumbelliferyl-B-D-glucuronide Trihydrate], 25 Grams CAS# 6160-80-1
    Manufacturer: Research Products International
    Mol. Wt:406.4 Common Name: 4-Methylumbelliferyl-β-D-glucuronide Trihydrate Formula: C16H16O9-3H2O Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.22, Cas#: 6160-80-1 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $2,213.00
  11. Tricine, Ultra Pure, N-Tris , Hydroxymethyl, Methyl, Glycine, 500 Grams
    Manufacturer: Research Products International
    Mol. Wt:179.17 Common Name: N-[Tris (Hydroxymethyl) Methyl] Glycine Formula: C6H13NO5 Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.23, Cas#: 1389475 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $355.30
  12. Tricine, Ultra Pure, N-Tris , Hydroxymethyl, Methyl, Glycine, 100 Grams
    Manufacturer: Research Products International
    Mol. Wt:179.17 Common Name: N-[Tris (Hydroxymethyl) Methyl] Glycine Formula: C6H13NO5 Dimensions: 3.50 x 3.75 x 3.50, Weight: 0.32, Cas#: 1389475 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $71.80
  13. Cefpodoxime Free Acid, 1 Gram CAS# 80210-62-4
    Manufacturer: Research Products International
    Mol. Wt:427.46 g/mol Common Name: Formula: C15H17N5O6S2 Dimensions: 1.25 x 1.75 x 1.25, Weight: 0.03, Cas#: 80210-62-4 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $250.00
  14. L-Ornithine HCl , L-2-5-Diaminopentanoic Acid, , 1 Kilogram CAS# 3184-13-2
    Manufacturer: Research Products International
    Mol. Wt:168.6 Common Name: L-2-5-Diaminopentanoic Acid Formula: C5H12N2O2-HCl Dimensions: 3.50 x 3.75 x 3.50, Weight: 2.5, Cas#: 3184-13-2 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $436.45
  15. L-Methionine, 500 Grams CAS# 63-68-3
    Manufacturer: Research Products International
    Mol. Wt:149.2 Common Name: Formula: C5H11NO2S Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.24, Cas#: 63-68-3 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $214.55
  16. PIPES DISODIUM SALT, 500G CAS# 27369851
    Manufacturer: Research Products International
    Mol. Wt:346.3 Common Name: Piperazine-N,N'-bis(2-ethanesulfonic acid)disodium salt Formula: C8H16N2Na2O6S2 Dimensions: 3.50 x 7.00 x 3.50, Weight: 1.24, Cas#: 27369851 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $515.30
  17. Imipenem Monohydrate, 25 MG CAS# 74431-23-5
    Manufacturer: Research Products International
    Mol. Wt:317.36 Common Name: Formula: C12H17N3O4S - H2O Dimensions: 1.25 x 1.75 x 1.25, Weight: 0.03, Cas#: 74431-23-5 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $489.50
  18. ADA, Biological Buffer, 25kg, CAS# 26239-55-4
    Manufacturer: Spectrum Chemical
    ADA, Biological Buffer (1 per EA )
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    $2,861.85
  19. 1-Methyl-2-Pyrrolidinone Biotech - 1L (Pack of 4), Biotech
    Manufacturer: Dawn Scientific
    1-Methyl-2-Pyrrolidinone Biotech - 1L (Pack of 4), Biotech (4 per PK )
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    was $299.62 Special Price $284.01
  20. Spermidine Free Base, 25 Grams CAS# 124-20-9
    Manufacturer: Research Products International
    Mol. Wt:145.25 g/mol Common Name: Spermidine Trihydrochloride Formula: C7H19N3 Dimensions: 1.63 x 3.00 x 1.63, Weight: 0.19, Cas#: 124-20-9 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $458.30
  21. Glycylglycine, Gly-Gly, 100 Grams CAS# 556-50-3
    Manufacturer: Research Products International
    Purity: >99% pKa (25°C): 8.0 pH range: 7.5 Heavy metals: >0.002% Soluble in: Water Store at: Room Temperature Usually ships within 24 hours. This product is sold for laboratory research use only. Mol. Wt:132.1 Common Name: Gly-Gly Formula: C4H8N2O3 Di (1 per EA)
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    $107.55
  22. HEPES, Free Acid, N-, 2-Hydroxyethyl, piperazine N'-, 2-ethanesulfonic acid, , 100 Grams CAS# 7365-45-9
    Manufacturer: Research Products International
    Mol. Wt:238.3 Common Name: [N-(2-Hydroxyethyl) piperazine N'-(2-ethanesulfonic acid)] Formula: C8H18N2O4S Dimensions: 3.50 x 3.75 x 3.50, Weight: 0.32, Cas#: 7365-45-9 Research or further manufacturing use only, not for food or drug use. (1 per EA)
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    $99.90
  23. 1-Methyl-2-Pyrrolidinone Biotech - 1L, Biotech, CAS#872-50-4
    Manufacturer: Dawn Scientific
    1-Methyl-2-Pyrrolidinone Biotech - 1L, Biotech, CAS#872-50-4 (1 per EA )
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    was $109.62 Special Price $103.91
  24. Tris(hydroxymethyl)aminomethan, 5.00 K Each
    Manufacturer: Reagents Inc
    Tris(hydroxymethyl)aminomethan, 5.00 K Each (1 per EA )
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    was $432.00 Special Price $315.00
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