Lab Procurement Services provides a wide range of solvent grades to meet the requirements of multiple lab and production applications. Please see our specific sections for ACS, Anhydrous, Electronic, High-Purity (including GC), HPLC, and USP-NF-FCC grades, as well as General Purpose products. 

Don't forget to check out our Chromatography Supplies and PPE Safety sections for other essential lab products!

Before ordering, match the grade to the work: HPLC and LC-MS grades are tested for properties such as low UV absorbance and low residue, ACS grade meets American Chemical Society reagent specifications, anhydrous grades have low water content for moisture-sensitive work, USP/NF/FCC grades serve pharmaceutical and food applications, and general purpose or technical grades suit cleaning and non-critical use. Then choose the container: amber glass, PVC-coated glass, poly bottles, Cubitainer, poly pails, or 20 L and 55 gal drums, often sold as 4 x 4 L cases. Check the SDS for storage and handling, and request a Certificate of Analysis (CoA) if your quality system needs lot-specific results.

Solvents: common questions

What is the difference between ACS grade and HPLC grade solvents?

ACS grade means the solvent meets or exceeds the purity specifications published by the American Chemical Society for reagent chemicals. HPLC grade solvents are tested for properties that matter in chromatography, such as low UV absorbance, low residue after evaporation and filtration to remove particles. A solvent can meet both, so check the label and specification sheet for the tests your method requires.

What does anhydrous mean for a solvent?

Anhydrous solvents have very low water content, usually stated as a maximum in ppm or percent on the specification sheet. They are used in reactions and analyses where water would interfere. Once a bottle is opened, the solvent can absorb moisture from the air, so keep containers tightly closed and use septum closures or dry handling if the water level is critical.

What documentation comes with laboratory solvents?

Every chemical has a Safety Data Sheet (SDS) describing hazards, storage, handling and disposal. Many manufacturers also provide a Certificate of Analysis (CoA) showing test results for a specific lot. Keep the SDS where staff can reach it, and request the CoA when your quality system or method validation requires lot-level records.

Can I order solvents for delivery to a home address?

No. Chemicals ship only to business addresses, and a company name is required at checkout. Many solvents ship directly from the manufacturer, so lead times vary by item. For drums or larger volumes, volume and quote pricing is available through the Contact Us page, and approved business accounts can pay by purchase order.

Solvents

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  1. Methyl Alcohol, Histological Grade, 4L, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methyl Alcohol, Histological Grade is also known by several other names including methyl alcohol, wood alcohol, and wood spirits. Methanol is known as the simplest alcohol. It is light, extremely volatile, colorless, flammable liquid with a strong odor. Methanol is highly toxic and it is not safe for human consumption. It is commonly used as an antifreeze, solvent, and a fuel as well as a denaturant for ethanol. Spectrum Chemical offers a wide range of chemicals and reagents, including histology-grade solvents, designed specifically for the medical laboratory study of the microscopic anatomy of cells and tissues.

    (1 per EA )
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    was $256.25 Special Price $227.47
  2. Isopropyl Rubbing Alcohol, 70 Percent, USP0
    Manufacturer: Spectrum Chemical
    Isopropyl Rubbing Alcohol, 70 Percent, USP is a colorless and flammable chemical compound also known as Rubbing Alcohol. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (6 per CS )
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    was $439.65 Special Price $395.05
  3. Acetonitrile, Reagent, ACS, 20L, CAS# 75-05-8
    Manufacturer: Spectrum Chemical
    Acetonitrile, Reagent, ACS is a colorless liquid with low viscosity and low chemical reactivity and is used in chemical labs as a polar aprotic solvent in organic synthesis. Acetonitrile is a medium-polarity solvent with a convenient liquid range that is miscible with water. As an ACS grade Reagent, Spectrum Chemical manufactured acetonitrile is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $892.95 Special Price $528.43
  4. Methylene Chloride, FCC0ML CS6, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, FCCis used to decaffeinate coffee and tea as well as to prepare extracts of hops and other flavorings. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

    (4 per CS )
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    was $3,037.40 Special Price $2,274.40
  5. Methylene Chloride, FCC, 4L, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, FCCis used to decaffeinate coffee and tea as well as to prepare extracts of hops and other flavorings. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

    (1 per EA )
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    was $810.60 Special Price $606.98
  6. Methylene Chloride, FCC, 500mL, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, FCCis used to decaffeinate coffee and tea as well as to prepare extracts of hops and other flavorings. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

    (1 per EA )
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    was $240.90 Special Price $180.39
  7. 2,2,4-Trimethylpentane, Reagent, ACS, 1L, CAS# 540-84-1
    Manufacturer: Spectrum Chemical
    2,2,4-Trimethylpentane, Reagent, ACS is a fuel additive, a non-polar solvent and a nephrotoxin. As a Reagent ACS grade reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA)
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    was $174.80 Special Price $103.44
  8. Dimethyl Sulfoxide, Reagent, 4L, CAS# 67-68-5
    Manufacturer: Spectrum Chemical
    Dimethyl Sulfoxide, Reagent is an organosulfur, colorless liquid and is also known as DMSO. Acting as an important polar aprotic solvent bcause of its ability to dissolve both polar and non-polar compounds and it's miscibility with a wide range of orgnic solvents inculding water. One of DMSO's main characteristics is its ability to penetrate human skin. In the field of biology it is used in PCR as an inhibitor of secondary structures in DNA templates and/or DNA primers. It can also be used as a cryoprotectant, reducing ice formation in cell media and thus preventing necrosis of the cell during the freezing process. As a Reagent Grade chemical, Spectrum Chemical manufactured dimethyl sulfoxide is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $1,901.50 Special Price $1,125.27
  9. Dimethyl Sulfoxide, Reagent, ACS, 500mL, CS6, CAS# 67-68-5
    Manufacturer: Spectrum Chemical
    Dimethyl Sulfoxide, Reagent, ACS is an organosulfur, colorless liquid and is also known as DMSO. Acting as an important polar aprotic solvent bcause of its ability to dissolve both polar and non-polar compounds and it's miscibility with a wide range of orgnic solvents inculding water. One of DMSO's main characteristics is its ability to penetrate human skin. In the field of biology it is used in PCR as an inhibitor of secondary structures in DNA templates and/or DNA primers. It can also be used as a cryoprotectant, reducing ice formation in cell media and thus preventing necrosis of the cell during the freezing process. As a Reagent Grade chemical, Spectrum Chemical manufactured dimethyl sulfoxide is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (6 per CS )
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    was $2,451.95 Special Price $1,468.82
  10. N,N-Dimethylformamide, Exceeds A.C.S. Specifications, HPLC Gradee, 4L, CAS# 68-12-2
    Manufacturer: Spectrum Chemical
    N,N-Dimethylformamide, Exceeds A.C.S. Specifications, HPLC Grade is a chemical compound that is flammable and contains a very strong odor. N,N-DIMETHYLFORMAMIDE has many uses, including as an analytical reagent in the laboratory as a HPLC mobile phase solvent. All HPLC and ultra-pure solvents offered by Spectrum are glass distilled, submicron filtered, and undergo rigorous specification testing to insure accurate, repeatable results.

    (1 per EA )
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    was $715.25 Special Price $582.00
  11. 2,2,4-Trimethylpentane, Exceeds A.C.S. Specifications, HPLC Grade, 4L, CAS# 540-84-1
    Manufacturer: Spectrum Chemical
    2,2,4-Trimethylpentane, Exceeds A.C.S. Specifications, HPLC Grade (1 per EA )
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    was $459.60 Special Price $373.97
  12. Methyl Alcohol, LC/MS Grade, 4L, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methyl Alcohol, LC/MS Grade (1 per EA )
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    $294.16
  13. Isopropyl Rubbing Alcohol, 70 Percent, USP, 4L, CAS# 67-63-0
    Manufacturer: Spectrum Chemical
    Isopropyl Rubbing Alcohol, 70 Percent, USP is a colorless and flammable chemical compound also known as Rubbing Alcohol. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (1 per EA )
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    was $329.50 Special Price $296.08
  14. Methylene Chloride, NF, 4L, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, NF is used as a carrier for pharmaceutical tablet coatings. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (1 per EA)
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    was $787.65 Special Price $589.78
  15. Methyl Alcohol, NF500ML CS6, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methyl Alcohol, NF is a solvent excipient. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (4 per CS )
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    was $1,015.30 Special Price $760.26
  16. Toluene, Reagent, ACS, 100mL, CAS# 108-88-3
    Manufacturer: Spectrum Chemical
    Toluene, Reagent, ACS As an ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $82.65 Special Price $48.91
  17. Chloroform, Stabilized with Amylene, Exceeds A.C.S. Specifications, HPLC Grade, 200L, CAS# 67-66-3
    Manufacturer: Spectrum Chemical
    Chloroform, Stabilized with Amylene, Exceeds A.C.S. Specifications, HPLC Grade is a colorless liquid used in chemical labs as a non-polar (mobile phase) solvent in high pressure liquid chromatography (HPLC). All HPLC and Ultra-pure solvents offered by Spectrum are glass distilled, submicron filtered, and undergo rigorous specification testing to insure accurate, repeatable results.

    (1 per EA )
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    $3,832.10
  18. Isopropyl Alcohol, Exceeds A.C.S. Specifications, HPLC Grade, 200L, CAS# 67-63-0
    Manufacturer: Spectrum Chemical
    Isopropyl Alcohol, Exceeds A.C.S. Specifications, HPLC Grade is a chemical compound that is flammable and contains a very strong odor. Isopropyl alcohol has many uses, including as an analytical reagent in the laboratory as a HPLC mobile phase solvent. All HPLC and ultra-pure solvents offered by Spectrum are glass distilled, submicron filtered, and undergo rigorous specification testing to insure accurate, repeatable results.

    (1 per EA )
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    $3,276.20
  19. Antimony Pentachloride, Reagent, 125g, CAS# 7647-18-9
    Manufacturer: Spectrum Chemical
    Antimony Pentachloride, Reagent, also known as Antimonic chloride or Antimony quintachloride, is a chemical compound used for the chlorination of organic compounds as a polymerization catalyst. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA )
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    $269.70
  20. Ethyl Acetate, Reagent, ACS, 20L, CAS# 141-78-6
    Manufacturer: Spectrum Chemical
    Ethyl Acetate, Reagent, ACS, is a colorless liquid that smells like pear drops. Abbreviated as EA, it can be found in glues, nail polish removers, cigarettes and other products. Primarily used as a diluent because of its low cost and toxicity, it is also used in laboratory settings for column chromatography and extractions. Prone to hydrolysis and transesterification, it is rarely used as a solvent. As an ACS grade Reagent, Spectrum Chemical manufactured Ethyl Acetate is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and pureness.

    (1 per EA )
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    was $1,209.35 Special Price $715.67
  21. Acetone, Reagent, ACS, 4L, CAS# 67-64-1
    Manufacturer: Spectrum Chemical
    Acetone, Reagent, ACS is a colorless, flammable, liquid. Due to its miscibility with water, it serves as an important solvent. Used as a polar aprotic solvent in a wide range of organic reactions, acetone does not form an azeotrope with water. Thanks to its low cost and volatility, it is also commonly used to clean laboratory glassware. Another characteristic of Acetone is that it can be cooled with dry ice to -78°C without freezing allowing this solvent to be used to conduct reactions at low temperature. As a Reagent ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA)
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    was $315.45 Special Price $186.68
  22. Petroleum Ether, B.R. 35 DEG -60 DEG C, Reagent, ACS, 4L, CAS# 8032-32-4
    Manufacturer: Spectrum Chemical
    Petroleum Ether, B.R. 35 DEG -60 DEG C, Reagent, ACS is also known as benzine and petroleum naphtha. It is a highly flammable, liquid hydrocarcbon that is mainly used as a nonpolar solvent. It is used as an essential ingredient in label removing products and as a low boiling solvent. As an ACS grade Reagent, Spectrum Chemical manufactured compound is used as the quality standard against which other substances are grade and has met the toughest regulatory standards for quality and pureness.

    (1 per EA )
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    was $268.85 Special Price $159.11
  23. Heptane, Reagent, 20L, CAS# 142-82-5
    Manufacturer: Spectrum Chemical
    Heptane, Reagent is a straight-chain alkane applied in laboratories as a non-polar solvent. In it's liquid form it is ideal to store and transport. Its reagent grade means its purity is suitable for use in analytical testing labs and chemical reactions.

    (1 per EA)
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    was $1,377.65 Special Price $815.27
  24. Toluene, Reagent, ACS, 500mL, CAS# 108-88-3
    Manufacturer: Spectrum Chemical
    Toluene, Reagent, ACS As an ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $108.15 Special Price $64.00
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