Lab Procurement Services provides a wide range of solvent grades to meet the requirements of multiple lab and production applications. Please see our specific sections for ACS, Anhydrous, Electronic, High-Purity (including GC), HPLC, and USP-NF-FCC grades, as well as General Purpose products. 

Don't forget to check out our Chromatography Supplies and PPE Safety sections for other essential lab products!

Before ordering, match the grade to the work: HPLC and LC-MS grades are tested for properties such as low UV absorbance and low residue, ACS grade meets American Chemical Society reagent specifications, anhydrous grades have low water content for moisture-sensitive work, USP/NF/FCC grades serve pharmaceutical and food applications, and general purpose or technical grades suit cleaning and non-critical use. Then choose the container: amber glass, PVC-coated glass, poly bottles, Cubitainer, poly pails, or 20 L and 55 gal drums, often sold as 4 x 4 L cases. Check the SDS for storage and handling, and request a Certificate of Analysis (CoA) if your quality system needs lot-specific results.

Solvents: common questions

What is the difference between ACS grade and HPLC grade solvents?

ACS grade means the solvent meets or exceeds the purity specifications published by the American Chemical Society for reagent chemicals. HPLC grade solvents are tested for properties that matter in chromatography, such as low UV absorbance, low residue after evaporation and filtration to remove particles. A solvent can meet both, so check the label and specification sheet for the tests your method requires.

What does anhydrous mean for a solvent?

Anhydrous solvents have very low water content, usually stated as a maximum in ppm or percent on the specification sheet. They are used in reactions and analyses where water would interfere. Once a bottle is opened, the solvent can absorb moisture from the air, so keep containers tightly closed and use septum closures or dry handling if the water level is critical.

What documentation comes with laboratory solvents?

Every chemical has a Safety Data Sheet (SDS) describing hazards, storage, handling and disposal. Many manufacturers also provide a Certificate of Analysis (CoA) showing test results for a specific lot. Keep the SDS where staff can reach it, and request the CoA when your quality system or method validation requires lot-level records.

Can I order solvents for delivery to a home address?

No. Chemicals ship only to business addresses, and a company name is required at checkout. Many solvents ship directly from the manufacturer, so lead times vary by item. For drums or larger volumes, volume and quote pricing is available through the Contact Us page, and approved business accounts can pay by purchase order.

Solvents

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  1. 2-Butanone, Reagent, ACS00LT, CAS# 78-93-3
    Manufacturer: Spectrum Chemical
    2-Butanone, Reagent, ACS is also known as 2-butanone and used widely as a solvent. As a Reagent ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (6 per CS )
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    was $961.95 Special Price $576.25
  2. iso-Butyl Alcohol, Reagent, ACS, 4L, CAS# 78-83-1
    Manufacturer: Spectrum Chemical
    iso-Butyl Alcohol, Reagent, ACS is mainly used as a solvent. As a Reagent ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $553.75 Special Price $327.69
  3. tert-Butyl Alcohol, Reagent, 4L, CAS# 75-65-0
    Manufacturer: Spectrum Chemical
    tert-Butyl Alcohol, Reagent, also known as 2-methyl-2-propanol, is a tertiary alcohol that is miscible with diethyl ether and ethanol. It is used as a solvent, ethanol denaturant and paint remover ingredient. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $399.80 Special Price $236.60
  4. Dimethyl Sulfoxide, Reagent, 500mL, CAS# 67-68-5
    Manufacturer: Spectrum Chemical
    Dimethyl Sulfoxide, Reagent is an organosulfur, colorless liquid and is also known as DMSO. Acting as an important polar aprotic solvent bcause of its ability to dissolve both polar and non-polar compounds and it's miscibility with a wide range of orgnic solvents inculding water. One of DMSO's main characteristics is its ability to penetrate human skin. In the field of biology it is used in PCR as an inhibitor of secondary structures in DNA templates and/or DNA primers. It can also be used as a cryoprotectant, reducing ice formation in cell media and thus preventing necrosis of the cell during the freezing process. As a Reagent Grade chemical, Spectrum Chemical manufactured dimethyl sulfoxide is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $512.50 Special Price $303.29
  5. Methanol, Absolute, Reagent, ACS, 20L, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methanol, Absolute, Reagent, ACS, is also called methyl alcohol or 'wood alcohol' it was one of the by products of distillation of wood. As the simplest alcohol around, it is light, flammable, colorless liquid with a strong and distinctive odor. It has many uses including acting as an antifreeze, (due to it's polar liquid properties), solvent, fuel as well as a denaturant for ethanol. As an ACS grade Reagent, Spectrum Chemical manufactured methanol is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and pureness.

    (1 per EA)
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    was $588.20 Special Price $352.36
  6. Dichloromethane, Reagent, ACS, 20L, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Dichloromethane, Reagent, ACS is a liquid, organic compound that is volatile and has a light sweet aroma. Although non-miscible with water, it is with most other organic solvents makeing it ideal in most chemical processes where a solvent is necessary. As an ACS grade Reagent, Spectrum Chemical manufactured Dichloromethane is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $1,216.05 Special Price $728.46
  7. 2,2,4-Trimethylpentane, Reagent, ACS, 4L, CAS# 540-84-1
    Manufacturer: Spectrum Chemical
    2,2,4-Trimethylpentane, Reagent, ACS is a fuel additive, a non-polar solvent and a nephrotoxin. As a Reagent ACS grade reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA)
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    was $428.05 Special Price $253.31
  8. Methyl Alcohol, Purified, 4L, CS4, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methyl Alcohol, Purified is a colorless, flammable substance used in chemical labs as a polar protic solvent in organic synthesis, as well as a carrier (mobile phase) solvent in high pressure liquid chromatography (HPLC). Methanol is the simplest type of alcohol and was, at one point, chiefly made from the distillation of wood, and is commonly referred to as wood alcohol, wood spirits or methyl alcohol.

    (4 per CS )
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    was $525.40 Special Price $314.73
  9. Acetone, NF, 4L, CAS# 67-64-1
    Manufacturer: Spectrum Chemical
    Acetone, NF is a low boiling, volatile organic compound. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (1 per EA )
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    was $483.05 Special Price $357.32
  10. Methylene Chloride, FCC, 1L, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, FCCis used to decaffeinate coffee and tea as well as to prepare extracts of hops and other flavorings. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

    (1 per EA)
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    was $314.85 Special Price $235.75
  11. Methylene Chloride, NF, 20L, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, NF is used as a carrier for pharmaceutical tablet coatings. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (1 per EA)
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    was $1,746.50 Special Price $1,046.23
  12. Ethylene Glycol, High Purity, CAS# 107-21-1
    Manufacturer: 710 Spirits Rocky Mtn Reagents
    1,2-Ethanediol (1 per EA)
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    $46.45
  13. Trimethylpentane (2,2,4-), ACS, 4 L, Amber Glass CAS# 540-84-1
    Manufacturer: 710 Spirits Rocky Mtn Reagents
    Isooctane (1 per EA)
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    $164.25
  14. Tetrahydrofuran, ACS, 4 L, Glass CAS# 109-99-9
    Manufacturer: 710 Spirits Rocky Mtn Reagents
    Tetrahydrofuran, ACS, 4 L, Glass CAS# 109-99-9 (1 per EA )
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    $107.65
  15. PRISTINE® Tetrahydrofuran, HPLC Grade, CAS# 109-99-9, 4 Liter, 4/case
    Manufacturer: Birch Biotech
    All shipments are FOB Morgantown, PA - shipping not included in price. Shipments with applicable products may incur a haz-mat fee. (4 per CS )
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    was $649.00 Special Price $538.91
  16. Kerosene, Red, 1.00 L Glass amber
    Manufacturer: Reagents Inc
    Kerosene, Red, 1.00 L Glass amber (1 per EA )
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    was $29.00 Special Price $21.60
  17. 1-Methyl-2-Pyrrolidinone ACS - ACS, 4X4L, CAS#872-50-4, CS4
    Manufacturer: Dawn Scientific
    1-Methyl-2-Pyrrolidinone ACS - ACS, 4X4L, CAS#872-50-4, CS4 (4 per CS )
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    was $789.62 Special Price $769.88
  18. Cyclohexane Reagent - 4L, Reagent, CAS#110-82-7
    Manufacturer: Dawn Scientific
    Cyclohexane Reagent - 4L, Reagent, CAS#110-82-7 (1 per EA )
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    was $129.62 Special Price $126.38
  19. Dichloromethane, CAS# 75-09-2, 1L
    Manufacturer: Dawn Scientific
    Dichloromethane, CAS# 75-09-2, 1L (1 per EA )
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    $99.62
  20. Dimethylformamide Reagent - Reagent, 4L, CAS#68-12-2
    Manufacturer: Dawn Scientific
    Dimethylformamide Reagent - Reagent, 4L, CAS#68-12-2 (1 per EA )
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    was $149.62 Special Price $145.88
  21. Dimethyl Sulfoxide ACS - ACS, 4X4L, CAS#67-68-5, CS4
    Manufacturer: Dawn Scientific
    Dimethyl Sulfoxide ACS - ACS, 4X4L, CAS#67-68-5, CS4 (4 per CS )
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    was $1,289.62 Special Price $1,257.38
  22. Dimethyl sulfoxide HPLC, CAS# 67-68-5, 4x4L
    Manufacturer: Dawn Scientific
    HPLC Grade Chromatography Solvent (4 per CS )
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    was $1,794.62 Special Price $1,749.75
  23. Cyclohexanone Reagent - 4L, Reagent, CAS#108-94-1
    Manufacturer: Dawn Scientific
    Cyclohexanone Reagent - 4L, Reagent, CAS#108-94-1 (1 per EA )
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    was $139.62 Special Price $136.13
  24. Dimethylformamide Reagent - Reagent, 4X4L, CAS#68-12-2, CS4
    Manufacturer: Dawn Scientific
    Dimethylformamide Reagent - Reagent, 4X4L, CAS#68-12-2, CS4 (4 per CS )
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    was $499.62 Special Price $487.13
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