Lab Procurement Services provides a wide range of solvent grades to meet the requirements of multiple lab and production applications. Please see our specific sections for ACS, Anhydrous, Electronic, High-Purity (including GC), HPLC, and USP-NF-FCC grades, as well as General Purpose products. 

Don't forget to check out our Chromatography Supplies and PPE Safety sections for other essential lab products!

Before ordering, match the grade to the work: HPLC and LC-MS grades are tested for properties such as low UV absorbance and low residue, ACS grade meets American Chemical Society reagent specifications, anhydrous grades have low water content for moisture-sensitive work, USP/NF/FCC grades serve pharmaceutical and food applications, and general purpose or technical grades suit cleaning and non-critical use. Then choose the container: amber glass, PVC-coated glass, poly bottles, Cubitainer, poly pails, or 20 L and 55 gal drums, often sold as 4 x 4 L cases. Check the SDS for storage and handling, and request a Certificate of Analysis (CoA) if your quality system needs lot-specific results.

Solvents: common questions

What is the difference between ACS grade and HPLC grade solvents?

ACS grade means the solvent meets or exceeds the purity specifications published by the American Chemical Society for reagent chemicals. HPLC grade solvents are tested for properties that matter in chromatography, such as low UV absorbance, low residue after evaporation and filtration to remove particles. A solvent can meet both, so check the label and specification sheet for the tests your method requires.

What does anhydrous mean for a solvent?

Anhydrous solvents have very low water content, usually stated as a maximum in ppm or percent on the specification sheet. They are used in reactions and analyses where water would interfere. Once a bottle is opened, the solvent can absorb moisture from the air, so keep containers tightly closed and use septum closures or dry handling if the water level is critical.

What documentation comes with laboratory solvents?

Every chemical has a Safety Data Sheet (SDS) describing hazards, storage, handling and disposal. Many manufacturers also provide a Certificate of Analysis (CoA) showing test results for a specific lot. Keep the SDS where staff can reach it, and request the CoA when your quality system or method validation requires lot-level records.

Can I order solvents for delivery to a home address?

No. Chemicals ship only to business addresses, and a company name is required at checkout. Many solvents ship directly from the manufacturer, so lead times vary by item. For drums or larger volumes, volume and quote pricing is available through the Contact Us page, and approved business accounts can pay by purchase order.

Solvents

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  1. Acetone Purified, 1.00 L Glass amber
    Manufacturer: Reagents Inc
    Acetone Purified, 1.00 L Glass amber (1 per EA )
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    was $70.50 Special Price $52.92
  2. Dichloromethane w/Amylene Preservative, >99.9%, GC/HPLC, Pesticide, ACS, 4x4L/CS
    Manufacturer: Chempure Brand
    Chempure believes buying American Made stands for quality. If Products have to be purchased outside North America, Once in our country, we uphold the rules of quality better than any other industrialized nation and will certify the established quality standards producing consistent quality products. Our primary objective is to source eighty percent of our materials from North American companies, certify outsourced materials and package materials to meet or exceed our high standards. Chempure is proud to make every effort in sourcing for both quality and value for the ChemPure Brand while utilizing American made products and supporting American jobs. (4 per CS )
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    was $628.97 Special Price $254.32
  3. N,N-Dimethyl formamide, CAS# 68-12-2, 1L
    Manufacturer: Dawn Scientific
    N,N-Dimethyl formamide, CAS# 68-12-2, 1L (1 per EA )
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    $184.62
  4. Methanol, CAS# 67-56-1, 500ml
    Manufacturer: Dawn Scientific
    Methanol, CAS# 67-56-1, 500ml (1 per EA )
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    $54.62
  5. Dimethyl sulfoxide - Lab, 4X4L, CAS#67-68-5, CS4
    Manufacturer: Dawn Scientific
    Dimethyl sulfoxide - Lab, 4X4L, CAS#67-68-5, CS4 (4 per CS )
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    was $1,279.62 Special Price $1,247.63
  6. 2,2,4-Trimethylpentane, Reagent, ACS, 1L, CAS# 540-84-1
    Manufacturer: Spectrum Chemical
    2,2,4-Trimethylpentane, Reagent, ACS is a fuel additive, a non-polar solvent and a nephrotoxin. As a Reagent ACS grade reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

    (1 per EA)
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    was $174.80 Special Price $103.44
  7. Dimethyl Sulfoxide, Reagent, 4L, CAS# 67-68-5
    Manufacturer: Spectrum Chemical
    Dimethyl Sulfoxide, Reagent is an organosulfur, colorless liquid and is also known as DMSO. Acting as an important polar aprotic solvent bcause of its ability to dissolve both polar and non-polar compounds and it's miscibility with a wide range of orgnic solvents inculding water. One of DMSO's main characteristics is its ability to penetrate human skin. In the field of biology it is used in PCR as an inhibitor of secondary structures in DNA templates and/or DNA primers. It can also be used as a cryoprotectant, reducing ice formation in cell media and thus preventing necrosis of the cell during the freezing process. As a Reagent Grade chemical, Spectrum Chemical manufactured dimethyl sulfoxide is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (1 per EA )
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    was $1,901.50 Special Price $1,125.27
  8. Dimethyl Sulfoxide, Reagent, ACS, 500mL, CS6, CAS# 67-68-5
    Manufacturer: Spectrum Chemical
    Dimethyl Sulfoxide, Reagent, ACS is an organosulfur, colorless liquid and is also known as DMSO. Acting as an important polar aprotic solvent bcause of its ability to dissolve both polar and non-polar compounds and it's miscibility with a wide range of orgnic solvents inculding water. One of DMSO's main characteristics is its ability to penetrate human skin. In the field of biology it is used in PCR as an inhibitor of secondary structures in DNA templates and/or DNA primers. It can also be used as a cryoprotectant, reducing ice formation in cell media and thus preventing necrosis of the cell during the freezing process. As a Reagent Grade chemical, Spectrum Chemical manufactured dimethyl sulfoxide is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and purity.

    (6 per CS )
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    was $2,451.95 Special Price $1,468.82
  9. N,N-Dimethylformamide, Exceeds A.C.S. Specifications, HPLC Gradee, 4L, CAS# 68-12-2
    Manufacturer: Spectrum Chemical
    N,N-Dimethylformamide, Exceeds A.C.S. Specifications, HPLC Grade is a chemical compound that is flammable and contains a very strong odor. N,N-DIMETHYLFORMAMIDE has many uses, including as an analytical reagent in the laboratory as a HPLC mobile phase solvent. All HPLC and ultra-pure solvents offered by Spectrum are glass distilled, submicron filtered, and undergo rigorous specification testing to insure accurate, repeatable results.

    (1 per EA )
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    was $715.25 Special Price $582.00
  10. 2,2,4-Trimethylpentane, Exceeds A.C.S. Specifications, HPLC Grade, 4L, CAS# 540-84-1
    Manufacturer: Spectrum Chemical
    2,2,4-Trimethylpentane, Exceeds A.C.S. Specifications, HPLC Grade (1 per EA )
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    was $459.60 Special Price $373.97
  11. Methyl Alcohol, LC/MS Grade, 4L, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methyl Alcohol, LC/MS Grade (1 per EA )
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    $294.16
  12. Isopropyl Rubbing Alcohol, 70 Percent, USP, 4L, CAS# 67-63-0
    Manufacturer: Spectrum Chemical
    Isopropyl Rubbing Alcohol, 70 Percent, USP is a colorless and flammable chemical compound also known as Rubbing Alcohol. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (1 per EA )
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    was $329.50 Special Price $296.08
  13. Methylene Chloride, NF, 4L, CAS# 75-09-2
    Manufacturer: Spectrum Chemical
    Methylene Chloride, NF is used as a carrier for pharmaceutical tablet coatings. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (1 per EA)
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    was $787.65 Special Price $589.78
  14. Methyl Alcohol, NF500ML CS6, CAS# 67-56-1
    Manufacturer: Spectrum Chemical
    Methyl Alcohol, NF is a solvent excipient. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP). (4 per CS )
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    was $1,015.30 Special Price $760.26
  15. Acetone, ACS, 16 oz, Poly CAS# 67-64-1
    Manufacturer: 710 Spirits Rocky Mtn Reagents
    Acetone, ACS, 16 oz, Poly CAS# 67-64-1 (1 per EA)
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    $19.85
  16. Methyl Alcohol, Technical, 5 gal, Metal Pail CAS# 67-56-1
    Manufacturer: 710 Spirits Rocky Mtn Reagents
    Assay: 99.5% Minimum; Methanol; Wood Alcohol; Carbino (1 per EA)
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    $59.20
  17. Cyclohexanone, 500.00 mL Glass amber
    Manufacturer: Reagents Inc
    Cyclohexanone, 500.00 mL Glass amber (1 per EA )
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    was $109.00 Special Price $82.08
  18. Pentane (n-Pentane), 500.00 mL Glass amber
    Manufacturer: Reagents Inc
    Pentane (n-Pentane), 500.00 mL Glass amber (1 per EA )
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    was $64.00 Special Price $47.52
  19. Petroleum Ether ACS, 1.00 L Glass amber
    Manufacturer: Reagents Inc
    Petroleum Ether ACS, 1.00 L Glass amber (1 per EA )
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    was $103.00 Special Price $77.76
  20. Isopropanol, 50% v/v, 1.00 L Poly natural
    Manufacturer: Reagents Inc
    Isopropanol, 50% v/v, 1.00 L Poly natural (1 per EA )
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    was $41.50 Special Price $31.32
  21. n-Propyl Alcohol ACS Reagent, 1.00 L Glass amber
    Manufacturer: Reagents Inc
    n-Propyl Alcohol ACS Reagent, 1.00 L Glass amber (1 per EA )
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    was $71.50 Special Price $54.00
  22. Methyl Ethyl Ketone (MEK), 500.00 mL Glass amber
    Manufacturer: Reagents Inc
    Methyl Ethyl Ketone (MEK), 500.00 mL Glass amber (1 per EA )
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    was $52.50 Special Price $38.88
  23. 2-Butoxyethanol 99%, 4.00 L Glass amber
    Manufacturer: Reagents Inc
    2-Butoxyethanol 99%, 4.00 L Glass amber (1 per EA )
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    was $218.00 Special Price $163.08
  24. Isopropyl Alcohol HPLC, CAS# 67-63-0, 4x4L
    Manufacturer: Dawn Scientific
    HPLC Grade Chromatography Solvent (4 per CS )
    Learn More
    was $349.62 Special Price $340.88
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