Zileuton, 5-LO inhibitor, 50mg, CAS# 111406-87-2
$130.00
N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea Purity: >98% Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1098-50mg-EA
Zileuton, 5-LO inhibitor, 50mg, CAS# 111406-87-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsZileuton is a reversible inhibitor (IC50 = 500nM RBL-1 cells, 300nM rat PMNL cells) of 5-Lipoxygenase (5-LO).1 It also inhibited leukotriene B4 biosynthesis (IC50's = 400nM rat PMNL, 400nM human PMNL and 900nM human whole blood).1 Zileuton suppressed prostaglandin biosynthesis via interference with arachidonic acid release in macrophages independent of 5-LO inhibition (IC50 = 13 µM PGE2 inhibition in LPS-stimulated whole blood).2 Zileuton was approved by the FDA in 1997 for the treatment of asthma (ZYFLO).
CAS Number: 111406-87-2
Manufacturer Part Number/SKU: 10-1098-50mg-EA
Tags: Focus Biomolecules